Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL p.Ser505Asn (p.S505N) ( ENST00000413998.7, ENST00000372470.9 )
MPL p.Ser505Asn (p.S505N) ( ENST00000372470.9, ENST00000413998.7 )
Associated Disease
thrombocytosis
Source Database
DisGeNET
Description
Evidence for a founder effect of the MPL-S505N mutation in eight Italian pedigrees with hereditary thrombocythemia.
Pubmed
19608689
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.138693270390077
Year of publication
2009
Drugs