Annotation Detail

Information
Associated Genes
KRAS
Associated Variants
KRAS p.Gly13Cys (p.G13C) ( ENST00000311936.8, ENST00000557334.6, ENST00000256078.10, ENST00000692768.1, ENST00000693229.1, ENST00000556131.2, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1 )
KRAS p.Gly13Arg (p.G13R) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000693229.1, ENST00000688940.1, ENST00000692768.1 )
KRAS p.Gly13Ser (p.G13S) ( ENST00000556131.2, ENST00000557334.6, ENST00000256078.10, ENST00000311936.8, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1, ENST00000685328.1, ENST00000686969.1 )
KRAS p.Gly13Cys (p.G13C) ( ENST00000256078.10, ENST00000311936.8, ENST00000693229.1, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1 )
KRAS p.Gly13Arg (p.G13R) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
KRAS p.Gly13Ser (p.G13S) ( ENST00000256078.10, ENST00000311936.8, ENST00000556131.2, ENST00000557334.6, ENST00000685328.1, ENST00000686969.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1 )
Associated Disease
adenocarcinoma
Source Database
DisGeNET
Description
KRAS mutations were found in 18 (7.2%) patients (15 in adenocarcinoma, 2 in squamous cell carcinoma and one in NSCLC-not otherwise specified), including an uncommon substitution G13C.
Pubmed
24040454
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.309144845927698
Year of publication
2013
Drugs