Annotation Detail
Information
- Associated Genes
- LGR6
- Associated Variants
-
LGR6 MUTATION
LGR6 MUTATION - Associated Disease
- Heart failure
- Source Database
- DisGeNET
- Description
- Down-regulation and desensitization of β-adrenergic receptors (β-AR) caused by G-protein-coupled receptor (GPCR) kinase 2 (GRK2) are prominent features of HF.
- Pubmed
- 24702056
- Section of the abstract supporting the evidence
- SIGNIFICANCE
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs