Annotation Detail
Information
- Associated Genes
- ADRB3
- Associated Variants
-
UCP2 p.Ala55Val (p.A55V)
(
ENST00000663595.2,
ENST00000310473.9,
ENST00000536983.5 )
UCP3 p.Val56Ala (p.V56A) ( ENST00000314032.9, ENST00000426995.2 )
ADRB2 p.Leu84= (p.L84=) ( ENST00000305988.6 )
ADRB2 p.Leu84= (p.L84=) ( ENST00000305988.6 )
ADRB2 p.Arg175= (p.R175=) ( ENST00000305988.6 )
ADRB2 p.Gly351= (p.G351=) ( ENST00000305988.6 )
LEP p.Thr71= (p.T71=) ( ENST00000308868.5 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
UCP2 p.Ala55Val (p.A55V) ( ENST00000310473.9, ENST00000536983.5, ENST00000663595.2 )
UCP3 p.Val56Ala (p.V56A) ( ENST00000314032.9, ENST00000426995.2 )
ADRB2 p.Leu84= (p.L84=) ( ENST00000305988.6 )
ADRB2 p.Leu84= (p.L84=) ( ENST00000305988.6 )
ADRB2 p.Arg175= (p.R175=) ( ENST00000305988.6 )
ADRB2 p.Gly351= (p.G351=) ( ENST00000305988.6 )
LEP p.Thr71= (p.T71=) ( ENST00000308868.5 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- We analyzed the obesity-related phenotypes body mass index (BMI), percentage of body fat, plasma leptin and insulin levels, fasting glucose concentration, and plasma lipid profile in 329 teenagers to investigate the effects of seven single nucleotide variants 252G/A, 523C/A and 1053G/C in ADRB2; Trp64Arg in ADRB3; 161C/T in PPARgamma; Ala55Val in UCP2; and 210C/T in UCP3.
- Pubmed
- 15959859
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.343344000998906
- Year of publication
- 2005
Drugs