Annotation Detail

Information
Associated Genes
KIT
Associated Variants
KIT p.Asp817Val (p.D817V) ( ENST00000288135.6, ENST00000412167.7, ENST00000686011.1, ENST00000687109.1, ENST00000687246.1, ENST00000687295.1, ENST00000689832.1, ENST00000689994.1, ENST00000690543.1, ENST00000692783.1 )
KIT p.Asp817Val (p.D817V) ( ENST00000686011.1, ENST00000687109.1, ENST00000288135.6, ENST00000412167.7, ENST00000687246.1, ENST00000687295.1, ENST00000689832.1, ENST00000689994.1, ENST00000690543.1, ENST00000692783.1 )
Associated Disease
Mastocytosis, Systemic
Source Database
DisGeNET
Description
The Asp816Val mutation in the catalytic domain of the c-kit receptor has been identified in patients with systemic mastocytosis.
Pubmed
9827716
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.28124280881607
Year of publication
1998
Drugs