Annotation Detail

Information
Associated Genes
FLT3
Associated Variants
FLT3 MUTATION
FLT3 MUTATION
Associated Disease
Graft-vs-Host Disease
Source Database
DisGeNET
Description
In a Cox-model of predefined variables, age, FLT3-ITD and >1 course of chemotherapy to reach CR were risk factors associated with inferior outcome, regardless of NPM1 mutational status, variations of transplant protocols, or development of graft-versus-host disease.
Pubmed
26351297
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs