Annotation Detail
Information
- Associated Genes
- ADRB2
- Associated Variants
-
ADRB1 p.Gly389Arg (p.G389R)
(
ENST00000369295.4 )
ADRB2 p.Glu27Gln (p.E27Q) ( ENST00000305988.6 )
ADRB2 p.Glu27Ter (p.E27*) ( ENST00000305988.6 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
ADRB1 p.Gly389Arg (p.G389R) ( ENST00000369295.4 )
ADRB2 p.Glu27Gln (p.E27Q) ( ENST00000305988.6 )
ADRB2 p.Glu27Ter (p.E27*) ( ENST00000305988.6 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Several common single nucleotide polymorphisms (SNPs) including Gly389Arg in beta(1)-AR, Gln27Glu in beta(2)-AR, and Trp64Arg in beta(3)-AR in humans could alter receptor function and these variations of beta-ARs were shown to have certain association with obesity.
- Pubmed
- 17611309
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.334657861092336
- Year of publication
- 2007
Drugs