Annotation Detail

Information
Associated Genes
AKR1B1
Associated Variants
AKR1B1 MUTATION
AKR1B1 MUTATION
Associated Disease
Focal glomerulosclerosis
Source Database
DisGeNET
Description
We observed that podocyte-specific deletion of Klf6 increased the susceptibility of a resistant mouse strain to adriamycin-induced (ADR-induced) focal segmental glomerulosclerosis (FSGS).
Pubmed
25689250
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs