Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 p.Tyr375Cys (p.Y375C) ( ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000440486.8, ENST00000481110.7 )
FGFR3 p.Tyr375Cys (p.Y375C) ( ENST00000412135.7, ENST00000340107.9, ENST00000352904.6, ENST00000440486.8, ENST00000481110.7 )
Associated Disease
Thanatophoric dysplasia, type 1
Source Database
DisGeNET
Description
We report on a case of thanatophoric dysplasia type 1 (TD1) due to a Tyr373Cys mutation in the fibroblast growth factor receptor 3 (FGFR3) gene with soft tissue syndactyly of the fingers and toes.
Pubmed
9843049
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Year of publication
1998
Drugs