Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 p.Arg248Cys (p.R248C) ( ENST00000481110.7, ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000440486.8 )
FGFR3 p.Arg248Cys (p.R248C) ( ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000440486.8, ENST00000481110.7 )
Associated Disease
thanatophoric dysplasia
Source Database
DisGeNET
Description
Somatic and germline mosaicism for a R248C missense mutation in FGFR3, resulting in a skeletal dysplasia distinct from thanatophoric dysplasia.
Pubmed
12833394
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.150289326019409
Year of publication
2003
Drugs