Annotation Detail
Information
- Associated Genes
- BCR
- Associated Variants
-
ABL1 p.Thr334Ile (p.T334I)
(
ENST00000372348.9,
ENST00000318560.6 )
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 ) - Associated Disease
- Myeloid Leukemia, Chronic
- Source Database
- DisGeNET
- Description
- It has been shown that the occurrence of the BCR-ABL1 T315I mutation leads to a very poor therapeutic outcome in chronic myelogenous leukemia (CML) patients treated with tyrosine kinase inhibitors.
- Pubmed
- 22489663
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.395567170261351
- Year of publication
- 2012
Drugs