Annotation Detail

Information
Associated Genes
ABL1
Associated Variants
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 )
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 )
Associated Disease
Myeloid Leukemia, Chronic
Source Database
DisGeNET
Description
The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia.
Pubmed
23065514
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.371405336343011
Year of publication
2013
Drugs