Annotation Detail

Information
Associated Genes
ABL1
Associated Variants
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 )
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 )
Associated Disease
Leukemia, Myeloid, Chronic-Phase
Source Database
DisGeNET
Description
The durable clearance of the T315I BCR-ABL mutated clone in chronic phase chronic myelogenous leukemia patients on omacetaxine allows tyrosine kinase inhibitor rechallenge.
Pubmed
21030353
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00977190739489092
Year of publication
2010
Drugs