Annotation Detail

Information
Associated Genes
ABL1
Associated Variants
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 )
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 )
Associated Disease
Philadelphia chromosome-positive acute lymphoblastic leukemia
Source Database
DisGeNET
Description
A phase 2 study of MK-0457 in patients with BCR-ABL T315I mutant chronic myelogenous leukemia and philadelphia chromosome-positive acute lymphoblastic leukemia.
Pubmed
25127392
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0195438147897818
Year of publication
2014
Drugs