Annotation Detail
Information
- Associated Genes
- ABL1
- Associated Variants
-
ABL1 p.Thr334Ile (p.T334I)
(
ENST00000372348.9,
ENST00000318560.6 )
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 ) - Associated Disease
- Myeloid Leukemia, Chronic
- Source Database
- DisGeNET
- Description
- Eight of 18 patients with BCR-ABL T315I-mutated chronic myelogenous leukemia (44%) had hematologic responses and one of three patients (33%) with Philadelphia chromosome-positive acute lymphoblastic leukemia obtained complete remission.
- Pubmed
- 22772060
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.371405336343011
- Year of publication
- 2013
Drugs