Annotation Detail
Information
- Associated Genes
- BCR
- Associated Variants
-
ABL1 p.Thr334Ile (p.T334I)
(
ENST00000372348.9,
ENST00000318560.6 )
ABL1 p.Thr334Ile (p.T334I) ( ENST00000372348.9, ENST00000318560.6 ) - Associated Disease
- Myeloid Leukemia, Chronic
- Source Database
- DisGeNET
- Description
- The BCR-ABL1 T315I mutation imparts resistance to tyrosine kinase inhibitors currently available for treatment of chronic myelogenous leukaemia.
- Pubmed
- 21486895
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.395567170261351
- Year of publication
- 2011
Drugs