Annotation Detail
Information
- Associated Genes
- CDK9
- Associated Variants
-
BRAF p.Leu637Ser (p.L637S)
(
ENST00000288602.11,
ENST00000496384.7,
ENST00000644969.2,
ENST00000646891.2 )
BRAF p.Leu637Ser (p.L637S) ( ENST00000646891.2, ENST00000644969.2, ENST00000288602.11, ENST00000496384.7 ) - Associated Disease
- Metastatic melanoma
- Source Database
- DisGeNET
- Description
- A patient with BRAF(L597S) mutant metastatic melanoma responded significantly to treatment with the MEK inhibitor, TAK-733.
- Pubmed
- 22798288
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2012
Drugs