Annotation Detail

Information
Associated Genes
MET
Associated Variants
MET p.His1112Pro (p.H1112P) ( ENST00000318493.11, ENST00000397752.8 )
MET p.His1112Arg (p.H1112R) ( ENST00000318493.11, ENST00000397752.8 )
MET p.Tyr1248Cys (p.Y1248C) ( ENST00000318493.11, ENST00000397752.8 )
MET p.His1112Pro (p.H1112P) ( ENST00000318493.11, ENST00000397752.8 )
MET p.His1112Arg (p.H1112R) ( ENST00000318493.11, ENST00000397752.8 )
MET p.Tyr1248Cys (p.Y1248C) ( ENST00000318493.11, ENST00000397752.8 )
Associated Disease
hereditary renal cell carcinoma
Source Database
DisGeNET
Description
Two were known as MET germ-line mutations (H1112R and Y1248C), which predispose to hereditary renal cell carcinoma.
Pubmed
12460923
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2002
Drugs