Annotation Detail

Information
Associated Genes
INS
Associated Variants
ADRB2 p.Gly16Arg (p.G16R) ( ENST00000305988.6 )
ADRB2 p.Gly16Arg (p.G16R) ( ENST00000305988.6 )
Associated Disease
Stress, Psychological
Source Database
DisGeNET
Description
Subjects who were homozygous both GG in the G-261A polymorphism at the alpha(2A)AR locus and GlyGly in the Arg16Gly polymorphism at the beta2-adrenergic (beta2AR) receptor loci had significantly higher insulin sensitivity and lower catecholamine levels during mental stress than subjects with other genotypes.
Pubmed
11467765
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2001
Drugs