Annotation Detail

Information
Associated Genes
CFH
Associated Variants
ENSG00000289697 c.3580+48C>T, CFH p.Arg1210Cys (p.R1210C) ( ENST00000696028.1, ENST00000696027.1, ENST00000696029.1, ENST00000695984.1, ENST00000695981.1, ENST00000695971.1, ENST00000695974.1, ENST00000367429.9, ENST00000695970.1, ENST00000695976.1 )
ENSG00000289697 c.3580+48C>T, CFH p.Arg1210Cys (p.R1210C) ( ENST00000367429.9, ENST00000695970.1, ENST00000695971.1, ENST00000695974.1, ENST00000695976.1, ENST00000695981.1, ENST00000695984.1, ENST00000696027.1, ENST00000696028.1, ENST00000696029.1 )
Associated Disease
Atypical Hemolytic Uremic Syndrome
Source Database
DisGeNET
Description
The complement factor H R1210C mutation is associated with atypical hemolytic uremic syndrome.
Pubmed
18235085
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.231606809293154
Year of publication
2008
Drugs