Annotation Detail

Information
Associated Genes
PIK3CD
Associated Variants
PIK3CD MUTATION
PIK3CD MUTATION
Associated Disease
glioblastoma
Source Database
DisGeNET
Description
ABT-263 (Navitoclax), an orally available small-molecule Bcl-2 inhibitor, and GDC-0941, a PI3K inhibitor, were used to treat established glioblastoma and glioblastoma neurosphere cells, alone or in combination.
Pubmed
24757258
Section of the abstract supporting the evidence
UNLABELLED
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0157436285806576
Drugs