Annotation Detail

Information
Associated Genes
ADRB2
Associated Variants
ADRB2 c.-47C>A ( ENST00000305988.6 )
ADRB2 c.-47C>T ( ENST00000305988.6 )
ADRB2 c.-20C>T ( ENST00000305988.6 )
ADRB2 p.Gly16Arg (p.G16R) ( ENST00000305988.6 )
ADRB2 p.Glu27Gln (p.E27Q) ( ENST00000305988.6 )
ADRB2 p.Glu27Ter (p.E27*) ( ENST00000305988.6 )
ADRB2 c.-47C>A ( ENST00000305988.6 )
ADRB2 c.-47C>T ( ENST00000305988.6 )
ADRB2 c.-20C>T ( ENST00000305988.6 )
ADRB2 p.Gly16Arg (p.G16R) ( ENST00000305988.6 )
ADRB2 p.Glu27Gln (p.E27Q) ( ENST00000305988.6 )
ADRB2 p.Glu27Ter (p.E27*) ( ENST00000305988.6 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
Four ADRB2 gene polymorphisms C19R (T-47C), T-20C, G16R (G+46A), Q27E (C+79G) were investigated in two studies: PEGASE, a study of moderate to severe hypertension (707 cases) conducted in France, and ECTIM, a case-control study of MI (1178 cases, 1187 controls) conducted in France, Northern Ireland and Scotland.
Pubmed
11821707
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.202735552176577
Year of publication
2002
Drugs