Annotation Detail
Information
- Associated Genes
- CYP1B1
- Associated Variants
-
SULT2B1 c.215-2819T>C
(
ENST00000201586.7,
ENST00000323090.4 )
SULT2B1 c.423+1736A>G ( ENST00000201586.7, ENST00000323090.4 )
SULT2B1 c.646-1246A>G ( ENST00000201586.7, ENST00000323090.4 )
SULT2B1 c.646-1246A>T ( ENST00000201586.7, ENST00000323090.4 )
COMT c.-921-780C>A ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 )
CYP1B1 p.Asn453Ser (p.N453S) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
CYP1B1 p.Asn453Thr (p.N453T) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
SULT2B1 c.215-2819T>C ( ENST00000201586.7, ENST00000323090.4 )
SULT2B1 c.423+1736A>G ( ENST00000201586.7, ENST00000323090.4 )
SULT2B1 c.646-1246A>G ( ENST00000201586.7, ENST00000323090.4 )
SULT2B1 c.646-1246A>T ( ENST00000201586.7, ENST00000323090.4 )
COMT c.-921-780C>A ( ENST00000361682.11, ENST00000403184.5, ENST00000403710.5, ENST00000406520.7, ENST00000407537.5, ENST00000428707.2, ENST00000676678.1, ENST00000678255.1, ENST00000678769.1, ENST00000678868.1 )
CYP1B1 p.Asn453Ser (p.N453S) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 )
CYP1B1 p.Asn453Thr (p.N453T) ( ENST00000490576.2, ENST00000494864.1, ENST00000610745.5, ENST00000614273.1, ENST00000714520.1 ) - Associated Disease
- prostate carcinoma
- Source Database
- DisGeNET
- Description
- According to a multivariate analysis, CYP1B1 (rs1800440), COMT (rs16982844), and SULT2B1 (rs12460535, rs2665582, rs10426628) were significantly associated with prostate cancer progression and hormone levels.
- Pubmed
- 24682418
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00570027931368637
- Year of publication
- 2015
Drugs