Annotation Detail

Information
Associated Genes
SOD1
Associated Variants
SOD1 p.Gly94Ala (p.G94A) ( ENST00000270142.11, ENST00000389995.4 )
SOD1 p.Gly94Ala (p.G94A) ( ENST00000270142.11, ENST00000389995.4 )
Associated Disease
Central neuroblastoma
Source Database
DisGeNET
Description
Impairment of nuclear factor-kappaB activation increased glutamate excitotoxicity in a motoneuron-neuroblastoma hybrid cell line expressing mutant (G93A) Cu/Zn-superoxide dismutase.
Pubmed
20623531
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00732893054616819
Year of publication
2010
Drugs