Annotation Detail

Information
Associated Genes
SOD1
Associated Variants
SOD1 p.His44Arg (p.H44R) ( ENST00000270142.11, ENST00000389995.4 )
SOD1 p.His44Arg (p.H44R) ( ENST00000270142.11, ENST00000389995.4 )
Associated Disease
amyotrophic lateral sclerosis
Source Database
DisGeNET
Description
Pro-oxidant copper-binding mode of the Apo form of ALS-linked SOD1 mutant H43R denatured at physiological temperature.
Pubmed
23837654
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.437872511657633
Year of publication
2013
Drugs