Annotation Detail

Information
Associated Genes
CASR
Associated Variants
CASR p.Pro39Ala (p.P39A) ( ENST00000490131.7, ENST00000498619.4, ENST00000638421.1, ENST00000639785.2 )
CASR p.Pro39Ser (p.P39S) ( ENST00000490131.7, ENST00000498619.4, ENST00000638421.1, ENST00000639785.2 )
CASR p.Pro39Ala (p.P39A) ( ENST00000490131.7, ENST00000498619.4, ENST00000638421.1, ENST00000639785.2 )
CASR p.Pro39Ser (p.P39S) ( ENST00000490131.7, ENST00000498619.4, ENST00000638421.1, ENST00000639785.2 )
Associated Disease
Hypocalciuric hypercalcemia, familial, type 1
Source Database
DisGeNET
Description
A 44-year-old female with familial hypocalciuric hypercalcemia (FHH) due to a homozygous missense mutation (Pro40Ala) in calcium sensing receptor (CaSR) gene has type 2 diabetes mellitus.
Pubmed
11095989
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.588425451698311
Year of publication
2000
Drugs