Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Gly623Asp (p.G623D) ( ENST00000442011.7, ENST00000508076.5 )
TGFBI p.Gly623Asp (p.G623D) ( ENST00000442011.7, ENST00000508076.5 )
Associated Disease
Familial Amyloid Polyneuropathy, Type V
Source Database
DisGeNET
Description
We report a novel corneal dystrophy phenotype secondary to the Gly623Asp mutation in the TGFBI gene that is associated with clinical features of both lattice corneal dystrophy and a Bowman's layer dystrophy.
Pubmed
15885785
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0081432561624091
Year of publication
2005
Drugs