Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Pro501Thr (p.P501T) ( ENST00000442011.7 )
TGFBI p.Pro501Ala (p.P501A) ( ENST00000442011.7 )
TGFBI p.Pro501Ser (p.P501S) ( ENST00000442011.7 )
TGFBI p.Pro501Thr (p.P501T) ( ENST00000442011.7 )
TGFBI p.Pro501Ala (p.P501A) ( ENST00000442011.7 )
TGFBI p.Pro501Ser (p.P501S) ( ENST00000442011.7 )
Associated Disease
Familial Amyloid Polyneuropathy, Type V
Source Database
DisGeNET
Description
Although the P501T of the BIGH3 gene found in this pedigree was precisely the one reported for lattice corneal dystrophy IIIA, no clinical feature was shown, even in the 85-year-old father.
Pubmed
11004271
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0081432561624091
Year of publication
2000
Drugs