Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124His (p.R124H) ( ENST00000442011.7 )
TGFBI p.Arg124Leu (p.R124L) ( ENST00000442011.7 )
TGFBI p.Arg124His (p.R124H) ( ENST00000442011.7 )
TGFBI p.Arg124Leu (p.R124L) ( ENST00000442011.7 )
Associated Disease
corneal dystrophy
Source Database
DisGeNET
Description
Many reports showed that even though the causative mutation is the same TGFBI R124H mutation, there are severe and mild phenotypes of the corneal dystrophy.
Pubmed
21628991
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0229966142567051
Year of publication
2011
Drugs