Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124His (p.R124H) ( ENST00000442011.7 )
TGFBI p.Arg124Leu (p.R124L) ( ENST00000442011.7 )
TGFBI p.Arg124His (p.R124H) ( ENST00000442011.7 )
TGFBI p.Arg124Leu (p.R124L) ( ENST00000442011.7 )
Associated Disease
Avellino corneal dystrophy
Source Database
DisGeNET
Description
In Avellino corneal dystrophy (Arg124His mutation of human transforming growth factor beta-induced gene [TGFBI]), highly reflective granular materials with irregular edges were observed in the superficial stroma.
Pubmed
17846354
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.485157395569526
Year of publication
2007
Drugs