Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
Associated Disease
Familial Amyloid Polyneuropathy, Type V
Source Database
DisGeNET
Description
In lattice corneal dystrophy (Arg124Cys and Leu527Arg mutations of TGFBI), highly reflective branching filaments of variable width were observed in the stroma.
Pubmed
17846354
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0081432561624091
Year of publication
2007
Drugs