Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
Associated Disease
corneal dystrophy
Source Database
DisGeNET
Description
Seven lattice CD patients from four unrelated families had an identical p.H626R mutation in TGFBI, three patients from a single lattice CD family carried a p.R124C substitution in TGFBI, and a granular type 2 CD pedigree was demonstrated to carry a heterozygous TGFBI p.M619K substitution.
Pubmed
24801599
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0229966142567051
Year of publication
2014
Drugs