Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
Associated Disease
Lattice corneal dystrophy Type I
Source Database
DisGeNET
Description
The R124C mutation of the TGFBI gene gives rise to lattice corneal dystrophy type I, which is characterized by irregularity, turbulence, and opacity of the corneal epithelium.
Pubmed
22080335
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.492681823117654
Year of publication
2012
Drugs