Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
Associated Disease
Lattice corneal dystrophy Type I
Source Database
DisGeNET
Description
Mutation analysis showed the classical Arg124Cys mutation in exon 4 of TGFBI/BIGH3, associated with LCDI.
Pubmed
16710170
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.492681823117654
Year of publication
2006
Drugs