Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg555Gln (p.R555Q) ( ENST00000442011.7 )
TGFBI p.Arg555Gln (p.R555Q) ( ENST00000442011.7 )
Associated Disease
corneal dystrophy
Source Database
DisGeNET
Description
Spontaneous and inheritable R555Q mutation in the TGFBI/BIGH3 gene in two unrelated families exhibiting Bowman's layer corneal dystrophy.
Pubmed
17980739
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0229966142567051
Year of publication
2007
Drugs