Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
TGFBI p.Arg555Trp (p.R555W) ( ENST00000442011.7 )
TGFBI p.Arg124Ser (p.R124S) ( ENST00000442011.7 )
TGFBI p.Arg124Cys (p.R124C) ( ENST00000442011.7 )
TGFBI p.Arg555Trp (p.R555W) ( ENST00000442011.7 )
Associated Disease
Lattice corneal dystrophy Type I
Source Database
DisGeNET
Description
We identified two TGFBI mutations: R124C (exon 4), which segregated with lattice type I corneal dystrophy, and R555W (exon 12), which segregated granular type I corneal dystrophy.
Pubmed
17768377
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.492681823117654
Year of publication
2007
Drugs