Annotation Detail

Information
Associated Genes
TGFBI
Associated Variants
TGFBI p.Arg555Trp (p.R555W) ( ENST00000442011.7 )
TGFBI p.Arg555Trp (p.R555W) ( ENST00000442011.7 )
Associated Disease
corneal dystrophy
Source Database
DisGeNET
Description
We investigated the role of TGFBI/BIGH3 in Groenouw corneal dystrophies by generating transgenic mice overexpressing TGFBI/BIGH3 containing the R555W mutation.
Pubmed
18568131
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0229966142567051
Year of publication
2008
Drugs