Annotation Detail

Information
Associated Genes
PDGFRA
Associated Variants
PDGFRA p.Val561Asp (p.V561D), ENSG00000282278 c.1018-56T>A ( ENST00000257290.10 )
PDGFRA p.Val561Asp (p.V561D), ENSG00000282278 c.1018-56T>A ( ENST00000257290.10 )
Associated Disease
Gastrointestinal Stromal Tumors
Source Database
DisGeNET
Description
The patient was found to carry a germline PDGFRA mutation (V561D) in the heterozygote state; it has only been seen rarely before and only in the somatic state in sporadic GISTs.
Pubmed
17566086
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.615647293561465
Year of publication
2007
Drugs