Annotation Detail

Information
Associated Genes
AGTR1
Associated Variants
AGTR1 MUTATION
AGTR1 MUTATION
Associated Disease
Diabetic Nephropathy
Source Database
DisGeNET
Description
Hypertension connected with renin-angiotensin system (RAS) hyperactivity and corresponding genotypes, angiotensinogen (AGT), angiotensine-converting enzyme (ACE) and angiotensin II type 1 receptor (AT1R), predispose the increasing risk of DN.
Pubmed
25109108
Section of the abstract supporting the evidence
BACKGROUND/AIM
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN,RGD
DisGENET score for the Gene Disease association
0.1129951513502
Drugs