Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
INS p.Tyr103Cys (p.Y103C), INS-IGF2 c.187+908A>G
(
ENST00000381330.5,
ENST00000397270.1,
ENST00000397262.5,
ENST00000250971.7,
ENST00000512523.1 )
INS p.Tyr103Cys (p.Y103C), INS-IGF2 c.187+908A>G ( ENST00000250971.7, ENST00000381330.5, ENST00000397262.5, ENST00000512523.1, ENST00000397270.1 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes.
- Pubmed
- 12788886
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.316412936945417
- Year of publication
- 2003
Drugs