Annotation Detail

Information
Associated Genes
TNF
Associated Variants
INS p.Tyr103Cys (p.Y103C), INS-IGF2 c.187+908A>G ( ENST00000381330.5, ENST00000397270.1, ENST00000397262.5, ENST00000250971.7, ENST00000512523.1 )
INS p.Tyr103Cys (p.Y103C), INS-IGF2 c.187+908A>G ( ENST00000250971.7, ENST00000381330.5, ENST00000397262.5, ENST00000512523.1, ENST00000397270.1 )
Associated Disease
Non-alcoholic Fatty Liver Disease
Source Database
DisGeNET
Description
G308A polymorphism of TNF-alpha gene is associated with insulin resistance and histological changes in non alcoholic fatty liver disease patients.
Pubmed
21057163
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00352874433704394
Year of publication
2010
Drugs