Annotation Detail

Information
Associated Genes
CYP3A4
Associated Variants
CYP3A4 MUTATION
CYP3A4 MUTATION
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
In conclusion, we have described for the first time a significant correlation of statin treatment and CYP3A4 2 and eNOS gene polymorphisms in T2D, suggesting a new genetic susceptibility factor for insulin resistance and hyperlipidemia in T2D.
Pubmed
24996290
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree,CTD_rat,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0930068037731162
Drugs