Annotation Detail

Information
Associated Genes
ADAMTS7
Associated Variants
rs974819
COL4A2 c.99+242A>G ( ENST00000480609.2, ENST00000360467.7, ENST00000649951.2, ENST00000617564.3, ENST00000714396.1, ENST00000714399.1, ENST00000619688.3, ENST00000649101.1, ENST00000494852.3, ENST00000650540.1, ENST00000400163.8 )
HHIPL1 c.1649-617T>C ( ENST00000330710.10, ENST00000357223.2 )
rs4380028 ( ENST00000379535.8 )
UBE2Z c.390+355C>T ( ENST00000360943.10 )
ADTRP c.153+4257T>C ( ENST00000229583.9, ENST00000414691.8 )
TCF21 c.*241C>G ( ENST00000237316.3 )
NC_000009.12:g.22125504G>C
rs974819
COL4A2 c.99+242A>G ( ENST00000360467.7, ENST00000400163.8, ENST00000480609.2, ENST00000494852.3, ENST00000617564.3, ENST00000619688.3, ENST00000649101.1, ENST00000649951.2, ENST00000650540.1, ENST00000714396.1, ENST00000714399.1 )
HHIPL1 c.1649-617T>C ( ENST00000330710.10, ENST00000357223.2 )
rs4380028 ( ENST00000379535.8 )
UBE2Z c.390+355C>T ( ENST00000360943.10 )
ADTRP c.153+4257T>C ( ENST00000229583.9, ENST00000414691.8 )
TCF21 c.*241C>G ( ENST00000237316.3 )
NC_000009.12:g.22125504G>C
Associated Disease
atherosclerosis
Source Database
DisGeNET
Description
The present study attempted to replicate the results for eight of these loci, CDKN2A/B(rs1333049), ADTRP(rs6903956), PDGFD(rs974819), TCF21(rs12190287), COL4A1-A2(rs4773144), HHIPL1(rs2895811), ADAMTS7(rs4380028) and UBE2Z(rs46522), in patients with pathologically defined atherosclerosis of the coronary arteries.
Pubmed
24573017
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00345279946692324
Year of publication
2015
Drugs