Annotation Detail

Information
Associated Genes
CETP
Associated Variants
rs12149545
CETP c.118+279G>A ( ENST00000200676.8, ENST00000379780.6, ENST00000566128.1 )
rs12149545
CETP c.118+279G>A ( ENST00000200676.8, ENST00000379780.6, ENST00000566128.1 )
Associated Disease
Acute coronary syndrome
Source Database
DisGeNET
Description
Among 3,717 patients with acute coronary syndrome or coronary artery bypass grafting (CABG) enrolled in a prospective genetic registry, we evaluated whether CETP gene variants previously shown to be associated with reduced CETP activity and high-density lipoprotein cholesterol increase (A allele for both TaqIB [rs708272] and rs12149545) are associated with a reduction in recurrent myocardial infarction (MI), recurrent revascularization, or death.
Pubmed
23891427
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00854418168799245
Year of publication
2013
Drugs