Annotation Detail
Information
- Associated Genes
- TRAF3
- Associated Variants
-
rs12147254
(
ENST00000539721.5,
ENST00000392745.8,
ENST00000351691.10,
ENST00000560371.5 )
rs12147254 ( ENST00000351691.10, ENST00000392745.8, ENST00000539721.5, ENST00000560371.5 ) - Associated Disease
- multiple myeloma
- Source Database
- DisGeNET
- Description
- Single nucleotide polymorphisms in the TRAF3 rs12147254 A allele and a specific haplotype 1 of TRAF3 [GAACAG] are associated with a decreased risk of multiple myeloma (odds ratio 0.709, P<0.001, and odds ratio 0.543, P<0.0001), while TRAF3 haplotype 4 [GGACAG] was associated with an increased risk of development of multiple myeloma (odds ratio 2.099, P=0.001).
- Pubmed
- 21228035
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00435300147494899
- Year of publication
- 2011
Drugs