Annotation Detail
Information
- Associated Genes
- AKR1B1
- Associated Variants
-
AKR1B1 MUTATION
AKR1B1 MUTATION - Associated Disease
- diabetes mellitus
- Source Database
- DisGeNET
- Description
- AR-TG mice homozygous for the transgene demonstrated a conditional cataract phenotype, whereby they developed lens vacuoles and cataract-associated structural changes only after induction of experimental diabetes; no such changes were observed in AR-TG heterozygotes or nontransgenic mice with or without experimental diabetes induction.
- Pubmed
- 25541468
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00706742019575203
Drugs