Annotation Detail

Information
Associated Genes
HGF
Associated Variants
EGFR p.Thr790Met (p.T790M) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Thr790Met (p.T790M) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Hepatocyte growth factor reduces susceptibility to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.
Pubmed
20008840
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00597172118576667
Year of publication
2010
Drugs