Annotation Detail
Information
- Associated Genes
- P2RX7
- Associated Variants
-
P2RX7 MUTATION
P2RX7 MUTATION - Associated Disease
- Diabetes
- Source Database
- DisGeNET
- Description
- In the Prevalence, Prediction, and Prevention of Diabetes in Botnia study, the minor allele in the missense functional variant rs1718119 (rs1718119>A348T) in P2RX7 was associated with increased insulin sensitivity and secretion, consistent with its known effect on increased pore function.
- Pubmed
- 25719930
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs