Annotation Detail

Information
Associated Genes
MET
Associated Variants
EGFR p.Thr790Met (p.T790M) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Thr790Met (p.T790M) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Reciprocal and complementary role of MET amplification and EGFR T790M mutation in acquired resistance to kinase inhibitors in lung cancer.
Pubmed
21062933
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0230402215184233
Year of publication
2010
Drugs