Annotation Detail
Information
- Associated Genes
- EGFR
- Associated Variants
-
EGFR p.Asp761Asn (p.D761N)
(
ENST00000455089.5,
ENST00000275493.7,
ENST00000450046.2 )
EGFR p.Asp761Tyr (p.D761Y) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Thr790Met (p.T790M) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Asp761Asn (p.D761N) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Asp761Tyr (p.D761Y) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 )
EGFR p.Thr790Met (p.T790M) ( ENST00000275493.7, ENST00000450046.2, ENST00000455089.5 ) - Associated Disease
- adenocarcinoma
- Source Database
- DisGeNET
- Description
- Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors.
- Pubmed
- 17085664
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.36
- Year of publication
- 2006
Drugs